Physiological activity in mediastinal teratomata.
نویسندگان
چکیده
The clinical details of two patients with benign mediastinal teratomata are presented. Both patients developed inflammation of the root of the neck, the first after a small dose of radiotherapy and the second after a larger dose of radiotherapy and exploration of the thoracic inlet. In both cases, exploration of the inflamed area was followed by persistent discharge of fluid which was sterile on culture. In the first case, this was found to have a high cholesterol, lipid, and amylase content. In both cases, a benign mixed teratoma, with contents including intestinal epithelium and pancreatic tissue, was removed at thoracotomy. The suggestion is made that leakage of digestive enzymes from pancreatic, intestinal or salivary tissue may be a cause of inflammation in and around teratomata, especially after surgical exploration. Early thoracotomy is advised when the condition is recognized.
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Teratomata arise, in order of frequency, in the ovaries, testes, anterior mediastinum, retroperitoneal region, presacral and coccygeal regions, pineal and other intracranial sites, neck, and abdominal viscera other than the gonads (Willis, 1951). Mediastinal teratomata rank third among all teratoid tumours and are the second most common mediastinal tumours (Inada and Nakano, 1958). The majority...
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عنوان ژورنال:
- Thorax
دوره 30 5 شماره
صفحات -
تاریخ انتشار 1975